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Wash your hands thoroughly with soap and water.
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If the suppository is soft, hold it under cool water or place it in the refrigerator for a few minutes to harden it before removing the wrapper.
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Remove the wrapper, if present.
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If you were told to use half of the suppository, cut it lengthwise with a clean, sharp blade.
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Put on a finger cot or disposable glove, if desired (available at a pharmacy).
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Lubricate the suppository tip with a water-soluble lubricant such as K-Y Jelly, not petroleum jelly (Vaseline). If you do not have this lubricant, moisten your rectal area with cool tap water.
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Lie on your side with your lower leg straightened out and your upper leg bent forward toward your stomach.
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Lift upper buttock to expose the rectal area.
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Insert the suppository, pointed end first, with your finger until it passes the muscular sphincter of the rectum, about 1/2 to 1 inch (1.25 to 2.5 centimeters) in infants and 1 inch (2.5 centimeters) in adults. If not inserted past this sphincter, the suppository may pop out.
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Hold buttocks together for a few seconds.
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Remain lying down for about 15 minutes to avoid having the suppository come out.
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Try to avoid having a bowel movement for about an hour so that the medication in the suppository can be absorbed into the body.
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Discard used materials and wash your hands thoroughly.